Strain phenomenon in protein aggregation
نویسندگان
چکیده
منابع مشابه
Strain phenomenon in protein aggregation
S of yeast and mammalian prions introduced the idea that the protein aggregates can exist in multiple stable conformations that can be propagated by seeding. These conformational states (aka strains) were shown to have distinct physical (secondary structure, stability) and biological (cytotoxicity, infectivity) properties. For mammalian prions they were also tied to differences in disease patho...
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ژورنال
عنوان ژورنال: Intrinsically Disordered Proteins
سال: 2013
ISSN: 2169-0707
DOI: 10.4161/idp.27130